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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC2
All Species:
19.7
Human Site:
S1544
Identified Species:
33.33
UniProt:
Q8NI27
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI27
NP_001075019.1
1593
182775
S1544
G
K
E
K
G
S
D
S
F
K
S
E
K
M
D
Chimpanzee
Pan troglodytes
XP_001139291
1595
183045
S1546
G
K
E
K
G
S
D
S
F
K
S
E
K
M
D
Rhesus Macaque
Macaca mulatta
XP_001086217
1593
182783
S1544
G
K
E
K
G
S
D
S
F
K
S
E
K
M
D
Dog
Lupus familis
XP_538164
1593
182721
S1544
G
K
E
K
G
G
D
S
F
K
S
E
K
M
D
Cat
Felis silvestris
Mouse
Mus musculus
B1AZI6
1594
182755
D1544
G
K
E
K
S
S
S
D
S
F
K
S
E
K
M
Rat
Rattus norvegicus
XP_233081
1594
182711
D1544
G
K
E
K
G
S
S
D
S
F
K
S
E
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510761
1648
188085
S1599
S
G
K
E
K
S
D
S
I
K
T
E
K
M
E
Chicken
Gallus gallus
XP_420332
1593
182430
S1545
S
G
K
E
K
G
D
S
I
K
A
E
K
M
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003847
1504
172218
M1456
R
R
K
D
E
N
G
M
T
R
V
P
A
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722763
1641
188490
Q1587
H
K
R
R
R
E
G
Q
N
G
E
E
E
L
R
Honey Bee
Apis mellifera
XP_393587
1354
156054
E1306
R
K
R
D
R
T
D
E
S
A
V
T
T
E
Q
Nematode Worm
Caenorhab. elegans
NP_498392
1437
164369
L1386
R
K
A
I
E
F
D
L
E
E
P
S
K
S
T
Sea Urchin
Strong. purpuratus
XP_795489
1592
178912
E1525
R
E
V
L
E
A
P
E
A
E
R
E
R
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173871
1804
205705
R1687
G
E
E
R
E
R
E
R
E
R
E
R
E
R
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
99.9
99
N.A.
97.4
97.4
N.A.
85.8
88.1
N.A.
72.9
N.A.
39.7
43.1
29.5
48.7
Protein Similarity:
100
99.3
100
99.3
N.A.
98.9
99
N.A.
91.4
93.9
N.A.
83.4
N.A.
59
60.2
48.5
65.1
P-Site Identity:
100
100
100
93.3
N.A.
33.3
40
N.A.
46.6
40
N.A.
0
N.A.
13.3
13.3
20
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
40
46.6
N.A.
73.3
66.6
N.A.
26.6
N.A.
33.3
20
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
0
8
8
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
15
0
0
58
15
0
0
0
0
0
0
29
% D
% Glu:
0
15
50
15
29
8
8
15
15
15
15
58
29
8
22
% E
% Phe:
0
0
0
0
0
8
0
0
29
15
0
0
0
0
0
% F
% Gly:
50
15
0
0
36
15
15
0
0
8
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
15
0
0
0
0
0
0
% I
% Lys:
0
65
22
43
15
0
0
0
0
43
15
0
50
15
0
% K
% Leu:
0
0
0
8
0
0
0
8
0
0
0
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
43
15
% M
% Asn:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
8
8
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% Q
% Arg:
29
8
15
15
15
8
0
8
0
15
8
8
8
8
15
% R
% Ser:
15
0
0
0
8
43
15
43
22
0
29
22
0
15
0
% S
% Thr:
0
0
0
0
0
8
0
0
8
0
8
8
8
0
8
% T
% Val:
0
0
8
0
0
0
0
0
0
0
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _